The Gene: An Intimate History Audiobook [Free Download by Trial]

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The Gene: An Intimate History by Siddhartha Mukherjee

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Summary

From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies-a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to "read" and "write" our own genetic information?The extraordinary Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. Throughout the narrative, the story of Mukherjee's own family-with its tragic and bewildering history of mental illness-cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation-from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Thomas Morgan to Crick, Watson and Rosa Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. As The New Yorker said of The Emperor of All Maladies, "It's hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion...An extraordinary achievement." Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or "write" the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.

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3 comments

  • Oswaldo Dahman
    •September 4, 2023 at 8:27 am
    Siddhartha Mukherjee thoroughly explored the history of the gene in "The Gene: An Intimate History," offering detailed accounts of various discoveries made since Darwin's time. While heavy on history, the book provides accessible scientific explanations for non-scientists. The reviewer found it interesting that Mukherjee discussed Lamarck, as it contrasts with another book they read. They now feel compelled to research further and verify the accuracy of the information. Mukherjee shares intriguing tidbits, both personal and scientific, throughout the rich history presented. Despite its length, the book maintains a fast-paced feel. One notable section focuses on Herman Muller, a scientist deeply involved in eugenics. Muller later realized that eugenics perpetuated oppression and became politically active, but faced backlash. The reviewer found this biography to be the highlight of the book. Mukherjee's analogy of genes using a rare syndrome provides insight into the complexities of gene expression. He emphasizes that not all genes are expressed all the time, as epigenetic modification plays a crucial role in gene silencing and activation. The book also delves into the relationship between genes, sex, and gender identity, presenting a complex model of gene expression and challenging traditional binary notions of gender. The discussion on race, IQ, and genes was well-balanced and thoroughly researched, according to the reviewer. While the reviewer wished for more examples of epigenetic modification, they acknowledge the book's length may have limited this. Overall, the book has a conservative tone, but still stands as a solid piece of work.
    0 0 •Reply
  • Will Appell
    •August 29, 2023 at 9:27 am
    I can't even begin to imagine how beautifully the author has described and imparted knowledge on this intricate topic. Although it's highly technical, the author weaves in personal anecdotes that make the science more relatable to everyday health concerns. It definitely raises important ethical considerations regarding biological and genetic science, which will undoubtedly play a significant role in our imminent future.
    0 0 •Reply
  • Lavona A.
    •August 28, 2023 at 9:35 am
    I absolutely loved 'The Gene: An Intimate History', it was as captivating as 'The Emperor of Maladies'. The way it unfolds is so gripping, it's like reading a thrilling novel. I genuinely hope that Dr. Mukherjee continues to write more books like this in the future.
    0 0 •Reply

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